| abstract |
(57) [Summary] (Corrected) [Structure] Formula, (In the formula, A is C 4 H 8 , C 5 H 10 , C 8 H 16 or C An aldose reductase inhibitor comprising an isobutyric acid derivative represented by a linear alkylene group represented by 10 H 20 ) or a pharmacologically acceptable salt thereof as an active ingredient. [Effect] As an aldose reductase inhibitor with low toxicity and high aldose reductase inhibitory effect, it is effective for the treatment of diabetes. In addition, the above isobutyric acid derivative, Since it also has a serum lipid lowering action, it is expected to be effective especially for complications of diabetes associated with hyperlipidemia. |