| abstract |
(57) Abstract: A volume-expandable preparation part (A) containing a water-swellable gel-forming polymer and a water-foaming foaming agent component dispersed in the polymer, and the preparation part (A ) Or a drug-containing formulation part (B) embedded in the formulation part (A) so that a part thereof is exposed, the formulation is further water-insoluble. A gastric suspension type drug sustained-release solid preparation coated with a water-permeable and elastic film made of a polymer. [Effect] By swelling and acquiring buoyancy of the volume-expanded formulation part, the drug can be reliably floated and retained in the stomach, and the drug can be released from the drug-containing formulation part with a stable release rate through the coating membrane. |