abstract |
(57) [Summary] [Purpose] To provide a novel sustained-release suppository. [Structure] A sustained-release suppository comprising a drug, a polyglycerin fatty acid ester having an HLB of 8 or less, and an oily base, and a method for producing the same. [Effects] Polyglycerin fatty acid ester, which is a sustained-release component, was not localized, and the sustained-release effect did not fluctuate between production lots. Furthermore, it was safe for living organisms and did not stimulate mucous membranes. The degree of sustained release can be adjusted by changing the amount of the release component added. The method for producing the present suppository is simple. |