| abstract |
(57) [Summary] (Modified) [Objective] To provide a quinazoline derivative useful in a method for treating cancer in the human or animal body. A quinazoline derivative of the formula I or a pharmaceutically acceptable salt thereof, a process for producing them, and a pharmaceutical composition having an anticancer effect, containing the compound or a pharmaceutically acceptable salt thereof. [Wherein m is 1, 2, 3; R 1 is OH, NH 2 , OCF 3 , C 1-4 alkyl, C 1-4 alkoxy and the like, particularly 6,7-dimethoxy is selected; Q is 6-quinolyl, 5-isoquinolyl, 5-quinoxalyl, 5-indolyl, 1H-indazole- 5-yl, 1H-benzotriazol-5-yl, 6-benzothiazolyl and the like 9 Membered or 10 membered bicyclic heterocyclic group or 9 membered or 10 membered Member of a bicyclic aryl group] |