| abstract |
(57) [Summary] (Modified) [Structure] An antibacterial agent containing an imidazole derivative represented by the general formula (I). [In the formula, R 1 represents hydrogen or C 1 -C 8 (halo) alkyl, R 2 represents hydrogen, C 1 -C 8 alkyl, C 5 -C 8 cycloalkyl, aryl or the like, or a nitrogen atom to which they are bonded. Forming a 4- to 8-membered ring with atoms; R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are hydrogen, halogen, C 1 to C 8 alkyl, C 1 to C 8 alkoxy, aralkyloxy, N Shows the O 2, NH 2 and the like; R 9 represents hydrogen, aryl, alkyl, heterocyclic, etc.; R 10 represents hydrogen, a C 1 -C 8 alkyl; n is 0, 1, 2] Effects ] Excellent antibacterial action against Helicobacter pylori. |