abstract |
(57) [Summary] [Object] To provide a compound having calpain inhibitory activity which is effective for the treatment of intractable diseases. [Structure] General formula; RA-CO-NH-CH (CH O) - (CH 2) amide derivatives represented by n-B. R Is a substituted amino group represented by the following general formula. Embedded image n is 0-5. B is a substituted or unsubstituted lower alkyl group, an aromatic hydrocarbon group, or a heterocyclic group. |