| abstract |
(57) Abstract: (Modified) PROBLEM TO BE SOLVED: To provide a substituted benzothienyl piperazine, use of these compounds as an antipsychotic drug, and a process for producing these compounds. SOLUTION: The following formula I [In the formula, X represents hydrogen, halogen, hydroxy, etc .; Y Is —CN or —NR 1 R 2 ; l is an integer of 1 or 2; m is an integer of 0, 1 or 2; n is also 1 when Y is CN. Except when 2, 3 or 4; R 1 is hydrogen, (C 1 -C 6 ) alkyl or (C 1 -C 6 ) alkylcarbonyl; R 1 2 is hydrogen, (C 1 -C 10 ) alkylcarbonyl, (C 3 To C 12 ) cycloalkylcarbonyl and the like; or R 1 and R 2 together with the nitrogen atom to which they are attached are (In the formula, A is C = O or CH 2 ; B is C = O, CHO H, CH 2 or CH 2 CH 2 ; and Z is hydrogen, halogen, hydroxy, etc.)]. |