| abstract |
(57) [Summary] [Constitution] General formula (I): [R 1 is-(C 1-4 alkyl) -O- (C 1-4 alkyl),-(C 1-4 alkyl) -S- (C 1-4 alkyl),-(C 1-4 alkyl) -O- (C 1 -4 alkyl) -O- (C1-4 alkyl),-(C1-4 alkyl) -O- (C1-4 alkyl) -S- (C1-4 alkyl),-(C1-4 alkyl) -S- (C1-4 alkyl) -O- (C1-4 alkyl),-(C1-4 alkyl) -S- (C1-4 alkyl) -S- (C1-4 Alkyl) group, R 2 is a hydrogen atom, a C1-4 alkyl group, n represents an integer of 1 to 3. And the acid addition salts and hydrates thereof. The compound of the general formula (I) and salts thereof are NO It has an S inhibitory effect and is useful for the treatment and / or prevention of shock, hypotension, rheumatoid arthritis, ulcerative colitis, ischemic encephalopathy, tumor, insulin-dependent diabetes, and the like. |