| abstract |
(57) [Problem] A piperidine derivative having an anxiolytic effect. The piperidine derivative of the general formula (I) exhibits effective sigma receptor activity. In addition, they show an anxiolytic property with a mild effect in animal studies, and therefore they are anxiety, psychosis, epilepsy, generalized seizures, motor struggles, motor impulse disorders, amnesia, cerebrovascular disorders, Alzheimer's senile dementia Is useful as a therapeutic agent for Parkinson's disease or Parkinson's disease. |