| abstract |
PURPOSE: To obtain the titled compound useful as a stomachic, drug for controlling intestinal function, and antispasmodic simply and inexpensively, by bringing an edible basidiomycetes capable of converting lithocholic acid into ursodeoxycholic acid into contact with lithocholic acid. n CONSTITUTION: An edible Basidiomycetes (Basidiomycetes preferably belonging to the genus Pleurotus, such as Pleurotus ostratus), capable of converting lithocholic acid shown by the formula I into ursodoxycholic acid shown by the formula II, is cultivated in a medium containing lithocholic acid preferably at 20W 35°C for 2W15 days by aerated culture, to give the desired ursodeoxycholic acid. n COPYRIGHT: (C)1985,JPO&Japio |