http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60178867-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 1984-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fba0afd793cfe5d64a863e9fd766c52d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59ecda24c60b96a5ba391dad361b78cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14936079debcb16ec11f7412ac2dce32 |
publicationDate | 1985-09-12^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S60178867-A |
titleOfInvention | Dihalogenoquinoline derivative |
abstract | NEW MATERIAL:A compound expressed by formula I [R is (substituted) cyclic amino except 3-substituted-1-piperazinyl; X 1 and X 2 are halogen]. n EXAMPLE: 1-Cyclopropyl-6, 8-difluoro-7-( 1-piperazinyl )-1, 4-dihydro-4-oxoquinoline- 3-carboxylic acid. n USE: A medicine, veterinary and fish drug, food preservative, germicide for external use and disinfectant. n PREPARATION: For example, ethyl cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate expressed by formula II is reacted with a cyclic amine expressed by the formula RH in a solvent, e.g. dimethyl sulfoxide, at 50W150°C for 1W3hr to form a 7-amino substitution product expressed by formula IIIwhich is directly as a crude product hydrolyzed or isolated and hydrolyzed with an acid or alkali to afford the aimed compound expressed by formula I . n COPYRIGHT: (C)1985,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62252772-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01125371-A |
priorityDate | 1984-02-24^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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