http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6314724-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df039a3bba404699e360a74b0bea24a6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 1986-07-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8de2531fdc1d334999f13c9ce13feca7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac11946b2c588bbaa772f8c06efa8600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d04a774ff4d4acc80ebc399a561631c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d6bab98906abeb5f91701768ea019f3 |
| publicationDate | 1988-01-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6314724-A |
| titleOfInvention | Prazosin preparation |
| abstract | PURPOSE: To provide the titled preparation containing crystalline prazosin and an enteric base (excluding acrylic resin). n CONSTITUTION: The objective prazosin preparation can be produced by mixing crystalline prazosin (e.g. hydrochloride: the crystal form of the compound may be α-, β- or γ-form, etc., or their mixture; preferably fine powder with an average particle diameter of ≤100μ, especially ≤30μ) and an enteric base (a pH- dependent polymeric substance capable or forming a film from an organic solvent, insoluble in water and soluble at ≥4.5 pH: e.g. cellulose acetate phthalate, shellac, etc.) at a weight ratio of 1:(0.05W50) and, if necessary, further mixing with a nonionic surfactant, excipient, disintegrant, colorant, etc. The dissolution rate of prazosin from the preparation is high and the released prazosin can be easily absorbed through digestive tracts. Prazosin is active to circulatory system (dilates peripheral vessel, decreases peripheral flow resistance and lowers pressure level) and is useful as a remedy for hypertension. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0523588-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0224121-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9457095-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8980321-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006500349-A |
| priorityDate | 1986-07-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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