http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63295507-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate | 1987-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_292fd289b8dfa5ea041321e5f07ebe97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b20ca91cfae4bffd5f3c7dc995c5ab83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7750ca479ea62c5cc1fad8029faf864b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adea2d8297bda58608c88311fa786289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a38f74d9fd664b08e223d5cb481f7399 |
| publicationDate | 1988-12-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63295507-A |
| titleOfInvention | Production of stabilized pharmaceutical preparation |
| abstract | PURPOSE: To advantageously obtain a stabilized pharmaceutical preparation of an unstable drug to absorb moisture in storage and to readily decompose, by blending the drug with a hardened oil, grinding, coating these particles with a vegetable oil, etc., under reduced pressure, granulating the coated particles by the use of both an excipient and a binder and drying. n CONSTITUTION: An unstable drug such as methyl methionine sulfonium chloride to absorb moisture during storage and to readily decompose is blended with 1W3 times as much as a hardened oil, ground and the mixed particles are coated with 1W3 times as much a vegetable oil or a middle-chain fatty acid triglyceride as the particles by spraying under 10W150Torr reduced pressure at 50W60°C. Then the coated particles are uniformly blended with 1W3 times as much as an excipient under 10W100Torr reduced pressure. Further the mixture is coated with about 5W8% solution of a binder under 100W150Torr reduced pressure at 45W55°C by spraying, granulated and dried under 10W100Torr reduced pressure at 45W55°C to inexpensively obtain a large amount of a stabilized pharmaceutical preparation of the drug. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016037537-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020090968-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018023309-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2020090968-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100966219-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112996515-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007508292-A |
| priorityDate | 1987-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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