| abstract |
Of the amino acid sequence of wild-type D-aminotransferase shown in SEQ ID NO: 2 in the amino acid sequence, the sites involved in efficiently producing (2R, 4R) -monatin (positions 100, 180-183, 243 and (2R, 4R) -monatin is efficiently converted from 4- (indol-3-ylmethyl) -4-hydroxy-2-oxoglutarate by replacing at least one amino acid residue at position 244) Can be modified to produce |