| abstract |
The present invention is a benzimidazole derivative represented by the following formula (I) or a pharmacologically acceptable pharmacologically acceptable thereof, which exhibits a sodium-dependent nucleoside transporter 2 activity inhibitory action and is useful for diseases caused by abnormal plasma uric acid levels. Or a prodrug thereof. The compound of the present invention is useful for the prevention or treatment of gout, hyperuricemia, urinary calculus, hyperuric acid nephropathy and the like. In the formula, n is 1 or 2; R 1 and R 2 are H, a halogen atom, a cyano group, a substituted alkyl group, a substituted aryl group, etc .; R 3 is H, a halogen atom, a substituted alkyl group, etc .; R 4 And R 5 represents H, a halogen atom, OH, etc .; R 6 and R X represent H or OH; R Y represents F or OH. |