| abstract |
PROBLEM TO BE SOLVED: To provide a nucleic acid expected to be useful for the treatment of shellfish allergy. SOLUTION: A base sequence encoding a signal peptide, a base sequence encoding an intracellular stabilization domain of LAMP, a base sequence encoding an allergen domain including Lit v 1, Lit v 4 and Lit v 3, a transmembrane base. Provided is a nucleic acid containing a base sequence encoding a domain and a base sequence encoding an endosome / lysosome target domain of LAMP in order, and containing a base sequence encoding a chimeric protein. [Selection diagram] None |