http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100213443-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb4984038bd9128b90e961411b77d3c9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
filingDate | 1997-06-13^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-08-02^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296b8417889f3a7ca73c2626c3494b91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0420bde48ed07ffe8baee5cf7d361f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42b469ac923f6fe644de10be7ea7e6ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ed42eee284690c10a466bb2fdc8110 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea065de46c226e6d472031ecde0cb150 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6d692db9df54b5a2716c6dc0e43bfdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d244d8bfb3feea815594419f7fa2406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d3682e4df2a3d2b87c93906be2d2ae4 |
publicationDate | 1999-08-02^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100213443-B1 |
titleOfInvention | New Manufacturing Method of Sepem Derivatives |
abstract | The present invention is esterified with an organic acid of the following general formula (III) in an organic solvent with a triazine derivative of the following general formula (V) to obtain an active ester compound of the following general formula (VI), VI) is subjected to an acylation reaction with a compound of the general formula (IV), to a novel process for the preparation of cefe derivatives of the general formula (I).n n n n n n n n In which R 1 is methyl or a general formula Wherein R 4 and R 5 may be the same or different from each other, and each independently represent hydrogen or methyl, R 6 represents hydrogen or a carboxy protecting group, and R 2 represents methyl, methoxymethyl, Pyridiniummethyl, 2- (4-methyl-thiazol-5-yl) ethenyl, (2, 5-dihydro-6-hydroxy-2-methyl-oxo-1, 2, 4-triazine-3 -Yl) thiomethyl or 1-methylpyrrolidiniomethyl, R 3 represents hydrogen, anion, metal atom or isopropoxycarbonyloxyethyl, t-butoxycarbonyloxymethyl, X is chlorine, Bromine, azido, mesyl or tosyl, R a and R b may be the same or different from each other and each independently represent hydrogen C 1 -C 4 alkyl, phenyl or substituted phenyl. |
priorityDate | 1997-06-13^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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