http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100466463-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-32 |
| filingDate | 1997-11-10^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-01-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-01-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100466463-B1 |
| titleOfInvention | Method for the preparation of citalopram |
| abstract | R 1 is CN, C 1-6 alkyloxycarbonyl or C 1-6 alkylaminocarbonyl. Reduction of the oxo group of the compound of formula 4 and ring closure of the resulting hydroxy compound, whereby corresponding 1- (4-fluorophenyl) -1,3-dihydroisobenzofuran is obtained, and then if R 1 is cyano, use it directly in the next step and if R 1 is C 1-6 alkyloxycarbonyl or C 1- If 6 alkylaminocarbonyl, convert to the corresponding compound wherein R 1 is cyano; And alkylating the resulting 5-cyano compound with halogenated 3-dimethyl-aminopropyl under basic conditions to obtain citalopram.n n n (Formula 4) |
| priorityDate | 1997-11-10^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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