http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100984643-B1

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Predicate Object
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-14
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
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filingDate 2007-08-30^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-10-01^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2010-10-01^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100984643-B1
titleOfInvention Zebrafish with Estrogen Reactive Reporter Gene and Screening Method of Estrogen Compound Using the Estrogen Reactive Reporter Gene
abstract The present invention relates to a zebrafish to which the estrogen reactive reporter gene is introduced and a method for screening an estrogen compound using the same. More specifically, the present invention relates to a zebrafish having a gene construct linked to a promoter of a zebrafish brain aromatase gene and a fluorescent protein reporter gene whose expression is regulated by the promoter and to which the promoter is regulated. The present invention relates to a method for screening an estrogen compound characterized by measuring the expression level of a reporter gene after treating a test substance.n n n The screening method of the present invention is a novel in vivo system for determining compounds with estrogen activity, which can mimic in vivo functions, allowing for the rapid and effective screening of compounds with estrogen activity in vivo. have.n n n n Estrogen Compounds, Zebrafish, Brain Aromatase Genes, Screening
priorityDate 2007-08-30^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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