http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101717304-B1

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
filingDate 2009-12-14^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-03-16^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-03-16^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101717304-B1
titleOfInvention Biomarkers for inhibitors with anti-angiogenic activity
abstract The present invention relates to a method of assessing the effect of integrin inhibitors and small molecule ATP orientated multi-kinase inhibitors on angiogenesis by the use of certain identified biomarkers. This method is particularly useful for measuring the efficacy of integrin inhibitors and small molecule ATP orientated multi-kinase inhibitors that are primarily used in the treatment of angiogenesis-related diseases such as cancer. In particular, the present invention relates to a biomarker associated with angiogenesis that allows analysis of target modulation in a non-invasive manner, preferably accessible in body fluids. The use of said biomarker for the screening of compounds having integrin inhibitory activity is also disclosed.
priorityDate 2008-12-23^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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