http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101982782-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-395 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 |
| filingDate | 2016-09-13^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-28^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-28^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101982782-B1 |
| titleOfInvention | Monoclonal antibody specifically binding to Thioredoxin-1 and use thereof |
| abstract | The present invention relates to an antibody specifically binding to thioredoxin 1 and its use, and more particularly to an antibody or its antigen-binding fragment specifically binding to thioredoxin 1, an antibody or an antigen- A recombinant vector comprising the nucleic acid molecule, a host cell, a method for producing the antibody or an antigen-binding fragment thereof, a kit for diagnosing breast cancer, and a method for providing information necessary for diagnosis of breast cancer . The monoclonal antibody of the present invention has excellent binding affinity to thioredoxin 1 and thus binds specifically to thioredoxin 1. Moreover, the monoclonal antibody can be useful for screening patients with breast cancer because of its high sensitivity and specificity. Furthermore, the detection of thioredoxin 1 using a monoclonal antibody that specifically binds to thioredoxin 1 of the present invention is more sensitive than the detection of other breast cancer diagnostic biomarkers CA15-3, The accuracy and reliability of diagnosis of breast cancer can be remarkably improved. |
| priorityDate | 2016-09-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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