http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102451403-B1

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
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filingDate 2020-04-01^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-10-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-10-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102451403-B1
titleOfInvention Promer for real-time detection for SNP analysis of ApoE gene and detection method using the same
abstract The present invention relates to a single nucleic acid for real-time detection of a single nucleotide polymorphism in an apolipoprotein E (ApoE) gene and a detection method using the same. More specifically, a method for detecting single nucleotide polymorphism in the ApoE gene in real time using a single nucleic acid having a structure of XYZ and comprising a nucleotide sequence capable of complementary binding to some or all of the nucleotide sequence of the ApoE gene in real time, and a kit therefor is about The method of detecting the SNP of the ApoE gene using a single nucleic acid (promer) cleaved only by the cleavage reagent according to the present invention in real time has an advantage in that it can be measured more accurately compared to the conventional method for detecting genetic variation using a probe. In addition, the E2/E2, E3/E3, E4/E4, E2/E3, E2/E4, and E3/E4 phenotypes of the ApoE gene can be distinguished quickly, accurately and simply, resulting in various diseases caused by the ApoE genotype, such as Alzheimer's and cardiovascular disease. It can be usefully used for diagnosis of related diseases, selection of therapeutic agents, and prognosis.
priorityDate 2020-04-01^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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