| abstract |
The present invention is directed to a tumor in which an endothelin is elevated in an individual (eg, prostate, lung, liver, chest, brain) by administering to the individual an effective amount of a compound of formula (I) or formula (Ia) as described herein. And tumors of the stomach, endometrium, testicles, thyroid gland, pituitary gland, bladder, kidney, pancreas and meninges). |