abstract |
The present invention provides a variety of thrombotic properties including substituted polycyclic aryl and heteroaryl pyridone compounds having the general formula (I) or pharmaceutically acceptable salts thereof, and coronary and cardiovascular diseases useful as inhibitors of the serine protease of the coagulation cascade: The present invention relates to compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of conditions:n n n n n n n n Wherein Ψ is selected from the group consisting of NH and NOH. |