Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce11117dccdc8c25e8a7518b8c1ff1de |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-033 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 |
filingDate |
2001-03-26^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec80b95b650c9c3757e90fdece28b71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fabe357c2cd63eb3082b8eaf3fd87e83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7202b71aeed0f87f20500bac4fe0d39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92eefaa37338c97687ca2c59d1c5d122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f26a3a9ff446983810372ef59898551a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e0dc924aabaf6c445b321bd90673e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a97b6f7e89e72de552ecc4b83cff21ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0da13bb9ad5b7629b55378fe1879db08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_497b0273ad6b6a79b8ef920a7b7a4a84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21a9545380400048f8a482f4c4e5e7ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ababf4291181f7c58d6b9b86469161c9 |
publicationDate |
2002-10-05^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20020075579-A |
titleOfInvention |
Novel method for preparing optically active pyridobenzoxazine carboxylic acid derivatives |
abstract |
The present invention relates to a novel process for the preparation of optically active pyridobenzoxazine carboxylic acid derivatives, comprising the application of a hydrolase purified from microorganisms or microorganisms to an opoxacin ester derivative which is a racemic mixture. Selectively hydrolyzing the floxacin ester derivative, separating the unhydrolyzed (S) -ofloxacin ester derivative, and hydrolyzing the isolated (S) -ofloxacin ester derivative It provides a method for producing a pyridobenzoxazine carboxylic acid derivative. Here, the microorganism that selectively hydrolyzes the (R) -ofloxacin ester derivative is Bacillus niacini EM001 (Accession No. KCTC 0965BP). The method of the present invention is a pyrodobenz having an optical activity by selectively removing the (R) -type ofloxacin ester with high selectivity as a simple, economical and environmentally friendly bioconversion technology. Oxazine carboxylic acid derivatives can be prepared in high yields. |
priorityDate |
2001-03-26^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |