http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050108358-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5053f82a7cd17c60822674b657cfb89e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2004-01-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f44b88f795e587053ca53040cb30f49f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e13f5514fa42ebfb804c3bcc5c58a4d |
| publicationDate | 2005-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20050108358-A |
| titleOfInvention | A process of preparing imatinib |
| abstract | The present invention relates to N- (2-methyl-5-aminophenyl-4- (3-pyridyl) -2-pyrimidine amine of formula (II) in the presence of an inert organic solvent. Reacting with 4-methyl-piperazino methyl) benzoyl halide to produce a hydrohalide salt of imatinib of formula (I), anhydrous or hydrated, and optionally with a free base or additional acid addition salt To a process for preparing imatinib of the free base or of the acid addition salt, comprising the step of:n n n n n n n n In formula (I), n represents 1, 2 or 3 and Hal represents bromo, chloro, fluoro or iodo. The present invention also relates to imatinib prepared by the above method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101286780-B1 |
| priorityDate | 2003-02-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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