| abstract |
The present invention, hyaluronic acid; Local anesthetics selected from the group consisting of local anesthetics of amide and ester type or combinations thereof; And an ascorbic acid derivative in an amount sufficient to prevent or reduce the effect on the viscosity and / or modulus of elasticity G 'of the composition caused by the local anesthetic upon heat sterilization. will be. The present invention further relates to non-medical uses, such as medical and cosmetic, and methods of making such compositions. |