| abstract |
The present invention relates to a compound of formula (I) for the delivery of a medicament containing a cationic lipid which facilitates, for example, (Wherein R 1 and R 2 are the same or different and each is an alkenyl or the like, X 3 is absent, alkyl or the like, X 1 and X 2 are each a hydrogen atom or together form a single bond or an alkylene, Y 1 is absent or an anion, L 1 is a single bond or the like, and R 3 is alkyl or the like), and a cationic lipid represented by the formula (II) (Wherein R 4 and R 5 are the same or different and are an alkenyl or the like, X 4 and X 5 are each a hydrogen atom, or together form a single bond or an alkylene, X 6 is absent, 2 is absent, and the anion, a and b are the same or different 0~3, L 4 is a single bond or the like, R 6 is alkyl, such as, L 2 and L 3 is -O-, -CO-O - or -O-CO-). The present invention also provides a lipid nanoparticle containing a cationic lipid. |