http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140125606-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56820bbb13a42311271e147869a36d30
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-585
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0091
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
filingDate 2013-04-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59c729545a2291a637112423468bfc1b
publicationDate 2014-10-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20140125606-A
titleOfInvention Pharmaceutical composition for preventing or treating bladder cancer comprising inducer or activator of BTG2 and screening method thereof
abstract The present invention relates to a pharmaceutical composition comprising a B cell translocation gene 2 (BTG2) expression promoter or a BTG2 activator as an active ingredient for the prevention or treatment of bladder cancer; and to a screening method of the pharmaceutical composition. The present invention provides a screening method of a therapeutic agent for bladder cancer, which comprises the steps of: treating bladder cancer cell lines with test substances; and selecting a test substance which has the increased expression level or activation level of the protein BTG2 in comparison with a control group. Furthermore, the present invention provides a BTG2 marker detection method for diagnosis of bladder cancer, which comprises the steps of: measuring the mRNA expression level of the gene BTG2 or the expression level of protein coded by the gene from a sample obtained from a bladder cancer patient; and making a comparison with a sample obtained from a normal control group.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160112165-A
priorityDate 2013-04-19^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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