http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150137899-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34fbcff83218187bec435a4fade23f9d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 |
| filingDate | 2014-05-30^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8319e38bbcfd7d1fddb5a6d6290d5b3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d18216288235d24f351156ee94b0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b5c41fd22c5749234adea521bb826a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07439a77edca11fffa1b928d3d40ba4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af0fccf43503bea5dabe6c7086697138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_572f02132a7ea456a67cad7201280199 |
| publicationDate | 2015-12-09^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20150137899-A |
| titleOfInvention | Improved Method for Preparing (R)-9-[2-(phosphonomethoxy)propyl]adenine |
| abstract | The present invention relates to a process for the preparation of novel (R) -9- [2- (phosphonomethoxy) propyl] adenine (PMPA) and provides high purity PMPA. Since the process for producing PMPA according to the present invention uses dialkyl methylsulfonyloxymethylphosphonate having low purity and high purity during the reaction as an intermediate, PMPA produced by this process has advantages of high purity due to few impurities Have. In addition, it does not use reagents sensitive to moisture and air contact, so it is safe, reproducible, and easy to handle, making it suitable for mass production. In addition, since acid addition salts of tenofovir disoproxyl and tenofovir disoproxyl can be prepared by using the high purity PMPA prepared by the method provided in the present invention, it is possible to produce a high purity, high quality raw drug It has advantageous advantages. |
| priorityDate | 2014-05-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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