| abstract |
The present invention relates to a human-derived ferritin monomer fragment and a fusion polypeptide using the same. More particularly, the present invention relates to a ferritin monomer fragment in which a part of the fourth loop of human-derived ferritin and a fifth helix are removed, And a fusion polypeptide in which a polypeptide or protein is fused at the N-terminal or C-terminal. The fusion polypeptide is excellent in its production efficiency, can form a protein cage by self-assembly and can encapsulate an effective substance therein, has a three-dimensional structure, The polypeptide or protein of the present invention exhibits excellent physiological activity and is effective for the diagnosis or treatment of diseases. |