Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J39-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J39-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 |
filingDate |
2015-07-24^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79bf4e94ea5ad469623119ec18517ced http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aba7862a2d14f0418f3037b9afed5d94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e9db69d6564d6eda28b0b17d610ae4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3709d78f965f2a2a47e24551fb9416d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_153224086409d90bd340911e2ba897f8 |
publicationDate |
2017-03-31^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20170035941-A |
titleOfInvention |
Purification platform for bispecific antibodies |
abstract |
High resolution protein A chromatography using chaotropic agonists and pH gradient or pH step elution buffers produces improved peak resolution between closely related molecular species. A bispecific antibody containing a protein A-binding-removed substituted CH3 domain paired with a protein A-binding CH3 domain is a protein A-binding-deleted CH3 domain pairing with a protein A-binding-removed substituted CH3 domain with high peak resolution, A single specific antibody containing a deduced substituted CH3 domain and a protein A-linked CH3 domain paired with a protein A-linked CH3 domain. Useful chaotropic agonists include magnesium chloride and calcium chloride. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023068740-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210084054-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021130717-A1 |
priorityDate |
2014-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |