abstract |
(I) for the treatment, prevention or management of cancer. Also disclosed is a method of treating, preventing or managing cancer, such as leukemia, comprising administering the compound. In certain embodiments, the method of treatment comprises administering a compound provided herein in combination with a second agent. Pharmaceutical compositions and single unit dosage forms containing such compounds are also disclosed. In formula (I), R 1 is optionally substituted cycloalkyl, aryl, heteroaryl or heterocyclyl; And R 2 and R 3 are each halo. |