| abstract |
The present invention relates to a composition for the prevention and treatment of bone diseases comprising an extract such as rock stone, the extract significantly inhibits osteoclast differentiation, and RANKL-induced osteoclastogenesis. ), significantly inhibits the reduction of osteoblast differentiation by free radicals and increases bone density, so osteoporosis, osteomalacia, osteopenia, bone atrophy, osteoarthritis ( Osteoarthritis) or periodontal disease (periodontal disease), including the prevention, improvement, and treatment of bone disease can be usefully used as an active ingredient of a pharmaceutical composition and health food. |