| abstract |
Nitroxoline prodrugs and uses thereof are provided. Specifically, there is provided a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a preparation method therefor, a composition containing the compound, and its use in the preparation of an anti-infectious and anti-tumor drug, The definition of the functional group in formula (I) is as shown in the specification. The compound represented by formula (I) has better pharmacokinetic parameters such as solubility, blood drug concentration, or half-life than nitroxolin. The compound represented by the formula (I) can reduce the frequency of drug administration, and can be applied to fields other than the urinary tract field. |