http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220024917-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-301 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
filingDate | 2020-06-25^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-03^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20220024917-A |
titleOfInvention | Electron detection of a target based on enzymatic cleavage of a reporter moiety |
abstract | Apparatus, systems and methods for target detection based on collateral cleavage of a reporter (730) by an enzyme (720) are disclosed. Biological gate transistor 106 may include a channel 710 and a reporter moiety 730 immobilized to the channel 710 . The state of the reporter moiety 730 is the output from the biological gate transistor 106 when an excitation condition is applied to the biological gate transistor 106 and a sample fluid 110 is applied in contact with the channel 710 . affects the signal. The sample fluid 110 may include an enzyme 720 configured to be activated in response to a target nucleic acid 722 to cleave the reporter moiety 730 . Excitation circuitry 1502 applies an excitation condition, and measurement circuitry 1504 measures the output signal from the biological gate transistor 106 . The analysis module 116 measures a parameter related to the presence of the target nucleic acid 722 based on the one or more measurements. |
priorityDate | 2019-06-25^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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