http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220091515-A

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filingDate 2020-10-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5cd1ce37b48eea464a3e0e95bdcc198
publicationDate 2022-06-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20220091515-A
titleOfInvention Methods, devices and marker material kits for multi-parameter X-ray fluorescence imaging
abstract A multi-parameter X-ray fluorescence imaging method in which detection sensitivity is maximized and radiation dose is minimized for a biological/biological sample (10) containing a first marker material comprises: irradiating the sample (10) with X-ray radiation (1) wherein the X-ray fluorescence (2) of the first marker material is excited, the spatially resolved detection of the X-ray fluorescence (2) of the first marker material and the X-ray fluorescence (2) of the first marker material ) from the determination of the distribution of a first marker material in a sample (10), wherein the sample (10) comprises at least one additional marker material excited by X-ray radiation (1) to X-ray fluorescence (2), wherein the second At least one of the first and one or more additional marker substances is provided for a specific interaction with the sample 10 or a ligand contained in the cell such that the fluorescent lines 3 of the one and one or more additional marker substances are different and traceable. a molecule and/or active ingredient molecule, wherein detection consists in spectrally resolved detection of the X-ray fluorescence (2) of the first and one or more additional marker substances, additionally of one or more additional marker substances in the sample (10). The at least one distribution is determined from the X-ray fluorescence (2) of the first and one or more additional marker substances. Also described herein is an optimized selection method for an imaging apparatus 100 for multi-parameter X-ray fluorescence imaging and a marker material kit for introducing a marker material into a sample 10 .
priorityDate 2019-10-25^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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