http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA06003365-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12
filingDate 2004-09-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91f98ba598f1394d254386dec72045f1
publicationDate 2006-06-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-PA06003365-A
titleOfInvention PROCESS OF PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES.
abstract The present invention relates to a novel process for the preparation of the compounds of the formula (I) comprising the catalytic asymmetric hydrogenation of a compound of the formula (II) in the presence of a catalyst comprising ruthenium and a diphosphine ligand chiral or comprising rhodium and a chiral diphosphine ligand, wherein R1, R2, R3 and R4 are as defined in the specification and claims. The compounds of the formula (I) and the corresponding salts and / or esters are pharmaceutically active substances.
priorityDate 2003-09-29^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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