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filingDate 1998-08-26^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75913d9cb16b017e30101b3de72b7b10
publicationDate 2002-05-31^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-502801-A
titleOfInvention Producing a 1-(3-cyclopentenyloxy-4-alkoxyphenyl)-4-oxocyclohexanecarbonitrile by cyclizing a 4-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-heptanediacid dialkyl ester
abstract A process for preparing a 1-(3-cyclopentyloxy-4-alkoxyphenyl)-4-oxocyclohexane carbonitrile of formula (I) comprises the cyclization of a 4-cyano-(3-cyclopentyloxy-4-alkoxyphenyl)-heptane diacid dialkyl ester of formula (II) in the presence of a base to a 5-cyano-(3-cyclopentyloxy-4-alkoxyphenyl)-oxocyclohexane carboxylic acid alkyl ester of formula (III), followed by the neutralization of this compound of formula (III) with an alkali metal hydrogen carbonate and then decarboxylation in the presence of an alkali metal carbonate to give a compound of formula (I) wherein R1 to R3 are independently alkyl.
priorityDate 1997-08-28^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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