titleOfInvention |
Use of pyrazolo[4,3-d]pyrimidin-7-ones, pyrazolo[3,4-d]pyrimidin-4-ones, quinazolin-4-ones, purin-6-ones, pyrido[3,2-d]pyrimidin-4-ones and tetracyclic derivatives to treat nitrate-induced tolerance |
abstract |
Use of cyclic guanosine mono-phosphate (cGMP) phosphodiesterase (PDE) inhibitors from the group of: pyrazolo[4,3-d]pyrimidin-7-ones, pyrazolo[3,4-d]pyrimidin-4-ones, quinazolin-4-ones, purin-6-ones, pyrido[3,2-d]pyrimidin-4-ones and their tetracyclic derivatives in the manufacture of medicaments to treat nitrate-induced tolerance. |