abstract |
Compounds of formula (I), pharmaceutically acceptable salts and prodrugs thereof which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases are disclosed, wherein X, R, R1, R2 and R3 have the definitions given in the description. |