| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b0cbf411eb729e344b4565059b397fa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-37 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate |
2004-08-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01b53e81a89af244fc7685e6f8e32db8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_940514f758973c9ba4f08340cdc477f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84c93dec445ec5a7c38a9801b1d48e85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a19296d22a3f4bb639f47fe5c11992da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_830603e45e6933a8f67ec939186b72a0 |
| publicationDate |
2009-06-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-545568-A |
| titleOfInvention |
Use of compounds that modulate beta-catenin/TCF activated transcription for manufacture of a medicamnet to treat cancer |
| abstract |
The present disclosure relates to compounds and methods for modulating transcription activated by beta-catenin/TCF, such as the selective inhibition of genes targeted by the Wnt/beta-catenin pathway. In particular, disclosed is a method for the manufacture of a medicament for the treatment of cancer wherein the method comprises the following steps: a) determining whether or not an agent increases the binding of p300 to beta-catenin and decreases the binding of CPB to beta-catanin; b) selecting an agent which increases the binding of p300 to beta-catenin and decreases the binding of CBP to beta-catenin; and c) combining the agent selected in step b) with one or more pharmaceutically acceptable carriers wherein the agent is a compound having a structure selected from formula (I). |
| priorityDate |
2003-08-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |