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filingDate 2008-05-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00b2daf32ec7680d51794b5c0515ec10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fc89a870c4b4775edba67993c38ab00
publicationDate 2012-07-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-582252-A
titleOfInvention A live attenuated antigenically marked classical swine fever vaccine comprising a FLAG epitope in the E1 glycoprotein region
abstract Disclosed is a recombinant classical swine fever virus (CSFV) mutant comprising a DNA sequence encoding a mutation in the El glycoprotein of said CSFV mutant, wherein the mutation comprises a 20 mer insertion (SEQ ID NO: 9) at nucleotide position 2429, wherein said 20 mer insertion comprises the FLAGTM epitope in the El glycoprotein of the CSFV mutant, said epitope consisting of the amino acid sequence, DYKDDDDK (SEQ ID NO:5) as the last eight amino acids of the insertion, wherein said recombinant CSFV mutant is a live attenuated CSFV and said FLAGTM epitope carried by said CSFV mutant is capable of being recognized by monoclonal antibodies specifically binding to said FLAG TM epitope, which serves as a positive mutation marker for said live attenuated CSFV mutant.
priorityDate 2007-05-22^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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