| abstract |
Disclosed are aminotetrahydropyran compounds of formula (I), wherein the substituents are as described within the specification. An example of a compound of formula (I) includes (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine. Further disclosed is a pharmaceutical composition which comprises a compound of formula (I) and a pharmaceutically acceptable carrier, and the use of a compound of formula (I) in the manufacture of a medicament for use in treating a condition selected from the group consisting of insulin resistance, hyperglycemia, and Type 2 diabetes. |