abstract |
Method for producing the acid Z, 7 [2 (2-naminothiazolyl-4) 2-methoxyiminoacertlamnino] 3 '(2-methyl-5,6-dioxo-1,2,5,6-tetrahyndro-1,2,4-triazinothio-3) deacetoxycephalospnoryne, formula I, also presentnin other tautomeric forms, characterized bynin that the acid Z, 7 [2 (2-aminothiazolyl-4) 2-methoxyiminoacetylaminoJ-cepnnlosporin acts with 2-methyl-5,6-dioxo1,2,5,6-tetrahydro-1,2,4-triazinothiolnornany tautomer thereof in a solventnorganic to Lewis acid, vntemperature from -10 to + 40 ° C, and the productnis isolated in a known manner, preferablynby treatment with water, changing the pH and drainingnthe separated sludge. |