http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-189808-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3662208bc972f8f1e472952e5abc57f5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A40-146 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8139 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-18 |
| filingDate | 1998-06-18^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94fbb64fd26618b07d5daf5a896d1814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eae11db3d7b50a45fae32427fa758a9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddfde6326906977c8216661903edbc21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05fb37773a5ae903f9935c522b2a5da0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a63627e30776e031f6448952884378db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7ec0857a1acfc46d40c1112d153f94f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_769964e2ba711dd7c2227c5aacede172 |
| publicationDate | 2005-09-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-189808-B1 |
| titleOfInvention | A method of protecting plants or parts of these plants from attack by one or more insects or nematodes, a transgenic plant and its sexual offspring resistant to the attack of one or more insects or nematodes, expression carrier, transgenic host cell transformed with a biologically functional expression carrier, and a repeated inhibitor peptide type I thyroglobulin domain |
| abstract | Equistatin, belonging to the type I repeated thyroglobulin domain, and known to be an inhibitor of cysteine proteases is found to also inhibit aspartic proteases with a different domain of the protein. The DNA encoding equistatin, and inhibitor or cysteine and aspartic proteases, is isolated from the sea anemone Actinia equina. The equistatin protein was found to be particularly active towards gut cysteine and aspartic proteases of a number of common insect pests of agricultural crops, such as Colorado potato beetle, corn rootworn, leafminer fly and thrips. P41 invariant chain fragment, another member of this family with only cysteine protease inhibitor activity was equally active towards the cysteine protease complement as was found for equistatin. Recombinant equistatin protein was found to be larvicidal against Colorado potato beetle and to strongly reduce fecundity of adult thrips. DNA encoding equistatin and other proteins containing similar type I repeated thyroglobulin domains may be cloned into vectors and used to transform plants thus conferring reduced susceptibility to damage by plant pests that have thiol and/or aspartic proteases as digestive enzymes including insects and nematodes and particularly Coleopteran, Dipteran and Thysanopteran insects. |
| priorityDate | 1997-06-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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