http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-1831500-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1da78fa3cacf25f8444d4001e3594b9f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
| filingDate | 1989-09-27^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2806090b29374f723efe3ac7ba0ab699 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab0b89c0e99c8d8d1cfcc047a9af994c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91fbe22e8c6a478eed65683fe1cbdd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e80c9da11b53d32ce5bd1522f486874 |
| publicationDate | 1993-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-1831500-C |
| titleOfInvention | Process of reducing a heterogeneity of secretory monoclonal antibodies |
| abstract | Usage: the invention relates to the field of biology and relates to a method for reducing the heterogeneity of secreted monoclonal antibodies. The proposal is pioneering. The invention consists in treating a culture fluid producing monoclonal antibodies with carboxypeptidase B at a ratio of secreted heterogeneous monoclonal antibodies: enzyme 100: 1, incubating the mixture for 5 hours by growing at a temperature of 22-23 ° C and isolating the target product in a homogeneous form. The positive effect of the proposal is to obtain homogeneous antibodies that can be isolated in pure form by gel filtration. |
| priorityDate | 1988-09-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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