http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2065863-C1

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filingDate 1991-12-24^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-08-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d1cd1d3ba42effc7e4dbbf39ad16063
publicationDate 1996-08-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2065863-C1
titleOfInvention Deacetylcolchicine derivatives, process for preparation thereof, and antitumor composition
abstract FIELD: medicine, as antitumor compound. SUBSTANCE: product: deacetylcolchicine derivative of formula i wherein R is C(O) acyl residue of saccharocarboxylic C 3 -C 7 -acid in which hydroxyl groups may be protected by acyl or ketal group. Reagent 1: deacetylcolchicine. Reagent 2: saccharocarboxylic acid R-COOH. Reaction conditions: amidation conditions. Structure of the compound of formula I: . EFFECT: improved properties of the antitumor composition. 6 cl, 4 tbl
priorityDate 1990-12-25^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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