abstract |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel derivatives of 4-aryl-1- -(indanemethyl or dihydrobenzothiophenemethyl)piperidine, -tetrahydropyridine or piperazine of the formula (I) where values R 1 -R 8 , Ar, X, Y, Z are given in p. 1 of the invention claim. Compounds acts on the central serotoninergic receptors and can be used as pharmaceutical compositions for treatment of patients with some psychic and neurological diseases. EFFECT: new compounds indicated above, valuable curative properties. 11 cl, 1 tbl, 19 ex |