abstract |
FIELD: medicine, oncology, pharmacy. n SUBSTANCE: invention relates to drugs, in particular, to a pharmaceutical composition used in treatment of breast cancer. Pharmaceutical composition comprises bisphosphonate, COX-2 inhibitor and taxotere for simultaneous, successive or separate using wherein bisphosphonate represents 2-(imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic acid (zolendronic acid) or its pharmacologically acceptable salt and wherein compound SC236 represents inhibitor of COX-2. n EFFECT: valuable medicinal properties of pharmaceutical composition. n 2 cl, 20 tbl, 21 ex |